Human Anatomy and Physiology - Circulatory and Excretory Systems MCQs 2026

50 questions with detailed answers · 22 from past papers · 5 quiz batches available

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Page 1 of 1Questions 1–10 of 50
  1. Q1easy

    Which of the following organs is NOT considered part of the excretory system

    1. AKidney
    2. BPancreas
    3. CSkin
    4. DLungs
    💡 Explanation:

    The pancreas is a digestive and endocrine organ; it does not function in excreting metabolic wastes.

  2. Q2hard

    The hormone erythropoietin, which stimulates red blood cell production, is secreted mainly by the

    1. AKidneys
    2. BLiver
    3. CPancreas
    4. DSpleen
    💡 Explanation:

    The kidneys detect low oxygen levels and release erythropoietin to stimulate bone marrow to make more red blood cells.

  3. Q3medium

    The renal artery that supplies blood directly to the kidney branches from the

    1. APulmonary artery
    2. BAorta
    3. CVena cava
    4. DHepatic artery
    💡 Explanation:

    The renal arteries branch directly off the abdominal aorta to supply the kidneys.

  4. Q4hard

    An artificial kidney (dialysis) machine works mainly on the principle of

    1. AOsmosis
    2. BFiltration only
    3. CDiffusion across a semi-permeable membrane
    4. DActive transport
    💡 Explanation:

    Dialysis removes wastes by diffusing them across a semi-permeable membrane down their concentration gradient.

  5. Q5hard

    The liver converts toxic ammonia into less toxic urea through the

    1. AKrebs cycle
    2. BOrnithine (urea) cycle
    3. CCalvin cycle
    4. DGlycolysis
    💡 Explanation:

    The ornithine cycle in liver cells combines ammonia with carbon dioxide to produce urea.

  6. Q6medium

    Sweat glands assist excretion mainly by removing

    1. AWater, salts and small amounts of urea
    2. BBile pigments
    3. CUric acid only
    4. DCarbon dioxide
    💡 Explanation:

    Sweat is a dilute solution containing water, salts, and trace urea, making skin a minor excretory organ.

  7. Q7easy

    The tube that carries urine out of the body during urination is the

    1. AUreter
    2. BUrethra
    3. CRenal vein
    4. DBowman's capsule
    💡 Explanation:

    The urethra conveys urine from the bladder to outside the body.

  8. Q8medium

    The inner region of the kidney containing the renal pyramids is the

    1. ACortex
    2. BCapsule
    3. CMedulla
    4. DHilum
    💡 Explanation:

    The renal medulla contains pyramidal structures made up mainly of loops of Henle and collecting ducts.

  9. Q9medium

    The outer region of the kidney is called the

    1. AMedulla
    2. BPelvis
    3. CCortex
    4. DCapsule
    💡 Explanation:

    The renal cortex is the outer layer of the kidney where most nephron filtration structures are located.

  10. Q10Past Paper · PPSC/FPSC/NTSmedium

    Birds and reptiles excrete nitrogenous waste mainly as

    1. AUric acid
    2. BUrea
    3. CAmmonia
    4. DCreatinine
    💡 Explanation:

    Uric acid is only slightly soluble and can be excreted as a semi-solid paste, conserving water, which suits egg-laying animals.

  11. Q11Past Paper · PPSC/FPSC/NTSmedium

    Fish primarily excrete nitrogenous waste in the form of

    1. AAmmonia
    2. BUrea
    3. CUric acid
    4. DCreatinine
    💡 Explanation:

    Fish are ammonotelic; ammonia diffuses directly into the surrounding water, which dilutes its toxicity.

  12. Q12Past Paper · PPSC/FPSC/NTShard

    Kidney stones are most commonly composed of

    1. AUric acid crystals
    2. BCholesterol
    3. CSodium chloride
    4. DCalcium oxalate
    💡 Explanation:

    Calcium oxalate is the most common mineral found in kidney stones.

  13. Q13Past Paper · PPSC/FPSC/NTSmedium

    Hemodialysis is a treatment used for patients suffering from

    1. ADiabetes
    2. BAnemia
    3. CKidney failure
    4. DHypertension
    💡 Explanation:

    Hemodialysis artificially filters waste and excess fluid from the blood when the kidneys can no longer do so.

  14. Q14Past Paper · PPSC/FPSC/NTSmedium

    The hormone that regulates water reabsorption in the kidney tubules is

    1. AInsulin
    2. BAldosterone
    3. CRenin
    4. DAntidiuretic hormone (ADH)
    💡 Explanation:

    ADH increases water permeability of the collecting duct, concentrating urine and conserving water.

  15. Q15hard

    Reabsorption of most filtered water and glucose mainly occurs in the

    1. AProximal convoluted tubule
    2. BDistal convoluted tubule
    3. CLoop of Henle
    4. DBowman's capsule
    💡 Explanation:

    The proximal convoluted tubule reabsorbs the bulk of filtered water, glucose, and ions back into the blood.

  16. Q16Past Paper · PPSC/FPSC/NTSmedium

    The main nitrogenous waste product excreted by humans is

    1. AUrea
    2. BAmmonia
    3. CUric acid
    4. DCreatine
    💡 Explanation:

    Humans are ureotelic, converting toxic ammonia into less toxic, water-soluble urea for excretion.

  17. Q17easy

    The tube that carries urine from each kidney to the bladder is the

    1. AUreter
    2. BUrethra
    3. CRenal vein
    4. DRenal artery
    💡 Explanation:

    Each ureter is a muscular tube that transports urine from the kidney to the bladder by peristalsis.

  18. Q18easy

    Urine is temporarily stored in the

    1. AUreter
    2. BUrinary bladder
    3. CUrethra
    4. DKidney
    💡 Explanation:

    The urinary bladder is a muscular sac that stores urine until it is voided.

  19. Q19medium

    The cup-shaped structure that surrounds the glomerulus is called the

    1. ALoop of Henle
    2. BRenal pelvis
    3. CCollecting duct
    4. DBowman's capsule
    💡 Explanation:

    Bowman's capsule collects the filtrate produced by the glomerulus as the first step of urine formation.

  20. Q20medium

    The part of the nephron where blood filtration first occurs is the

    1. ALoop of Henle
    2. BCollecting duct
    3. CDistal convoluted tubule
    4. DGlomerulus
    💡 Explanation:

    The glomerulus is a tuft of capillaries where blood pressure forces fluid and solutes into Bowman's capsule.

  21. Q21Past Paper · PPSC/FPSC/NTSmedium

    The scientist credited with discovering the circulation of blood is

    1. ALouis Pasteur
    2. BRobert Koch
    3. CWilliam Harvey
    4. DEdward Jenner
    💡 Explanation:

    William Harvey described the systemic circulation of blood pumped by the heart in 1628.

  22. Q22hard

    The opening in the fetal heart that allows blood to bypass the non-functional lungs is the

    1. AForamen ovale
    2. BDuctus deferens
    3. CSemilunar valve
    4. DInterventricular septum
    💡 Explanation:

    The foramen ovale lets blood pass directly from the right atrium to the left atrium in the fetus.

  23. Q23easy

    Which of the following is NOT a normal component of blood

    1. APlasma
    2. BPlatelets
    3. CLeukocytes
    4. DSynovial fluid
    💡 Explanation:

    Synovial fluid lubricates joints and is not a component of blood.

  24. Q24medium

    The lymphatic system helps return excess tissue fluid to

    1. AThe kidneys
    2. BThe liver
    3. CThe bloodstream
    4. DThe lungs
    💡 Explanation:

    Lymphatic vessels collect excess interstitial fluid and return it to the venous blood circulation.

  25. Q25medium

    Blood is classified as which type of tissue

    1. AEpithelial tissue
    2. BConnective tissue
    3. CMuscular tissue
    4. DNervous tissue
    💡 Explanation:

    Blood is a fluid connective tissue consisting of cells suspended in plasma.

  26. Q26Past Paper · PPSC/FPSC/NTSmedium

    The average lifespan of a human red blood cell is about

    1. A10 days
    2. B120 days
    3. C1 year
    4. D7 days
    💡 Explanation:

    Red blood cells circulate for roughly 120 days before being broken down, mainly in the spleen.

  27. Q27Past Paper · PPSC/FPSC/NTSmedium

    Hardening and narrowing of arteries due to fatty deposits is called

    1. AThrombosis
    2. BVaricose veins
    3. CAneurysm
    4. DAtherosclerosis
    💡 Explanation:

    Atherosclerosis is caused by plaque buildup on artery walls, reducing blood flow.

  28. Q28Past Paper · PPSC/FPSC/NTSeasy

    The medical condition of persistently high blood pressure is called

    1. AHypotension
    2. BAnemia
    3. CArrhythmia
    4. DHypertension
    💡 Explanation:

    Hypertension is sustained elevated arterial blood pressure and a major risk factor for heart disease.

  29. Q29easy

    Blood pressure is measured using an instrument called a

    1. AStethoscope
    2. BThermometer
    3. CSphygmomanometer
    4. DBarometer
    💡 Explanation:

    A sphygmomanometer measures systolic and diastolic blood pressure in the arteries.

  30. Q30medium

    Which blood vessel carries oxygenated blood from the lungs to the heart

    1. APulmonary artery
    2. BVena cava
    3. CAorta
    4. DPulmonary vein
    💡 Explanation:

    The pulmonary vein is unusual in carrying oxygenated blood, from the lungs into the left atrium.

  31. Q31medium

    The heart is enclosed by a protective double-layered membrane called the

    1. APeritoneum
    2. BPleura
    3. CMeninges
    4. DPericardium
    💡 Explanation:

    The pericardium encloses the heart and reduces friction as it beats.

  32. Q32easy

    White blood cells primarily function in

    1. AOxygen transport
    2. BBody defense and immunity
    3. CBlood clotting
    4. DNutrient transport
    💡 Explanation:

    Leukocytes defend the body against infections and foreign invaders.

  33. Q33Past Paper · PPSC/FPSC/NTShard

    The Rh blood factor was first discovered in which animal

    1. AChimpanzee
    2. BRhesus monkey
    3. CGuinea pig
    4. DRabbit
    💡 Explanation:

    The Rh antigen is named after the Rhesus monkey, in which it was first identified.

  34. Q34easy

    Which blood vessels have walls only one cell thick, allowing exchange of substances with tissues

    1. AArteries
    2. BVeins
    3. CCapillaries
    4. DVenules
    💡 Explanation:

    Capillaries have thin, permeable walls that permit diffusion of gases and nutrients between blood and tissues.

  35. Q35medium

    The straw-colored fluid part of blood, obtained after removing the blood cells, is called

    1. APlasma
    2. BSerum
    3. CLymph
    4. DChyme
    💡 Explanation:

    Plasma is the liquid matrix of blood containing water, proteins, and dissolved substances, once the cells are removed.

  36. Q36Past Paper · PPSC/FPSC/NTSmedium

    Blood circulation between the heart and the lungs is known as

    1. ASystemic circulation
    2. BPortal circulation
    3. CPulmonary circulation
    4. DCoronary circulation
    💡 Explanation:

    Pulmonary circulation carries deoxygenated blood to the lungs and returns oxygenated blood to the heart.

  37. Q37Past Paper · PPSC/FPSC/NTSmedium

    The instrument used to record the electrical activity of the heart is the

    1. ASphygmomanometer
    2. BStethoscope
    3. CElectrocardiograph (ECG)
    4. DSpirometer
    💡 Explanation:

    An ECG records the electrical signals that trigger each heartbeat, helping detect arrhythmias.

  38. Q38Past Paper · PPSC/FPSC/NTSeasy

    Normal human blood pressure is approximately

    1. A140/90 mmHg
    2. B120/80 mmHg
    3. C100/60 mmHg
    4. D160/100 mmHg
    💡 Explanation:

    A reading of 120/80 mmHg represents normal systolic over diastolic pressure in a healthy adult.

  39. Q39Past Paper · PPSC/FPSC/NTSmedium

    The natural pacemaker of the heart is the

    1. ASinoatrial (SA) node
    2. BAtrioventricular (AV) node
    3. CBundle of His
    4. DPurkinje fibers
    💡 Explanation:

    The SA node, located in the right atrium, initiates the electrical impulse that sets the heart rhythm.

  40. Q40medium

    Deoxygenated blood is carried from the heart to the lungs by the

    1. AAorta
    2. BPulmonary vein
    3. CVena cava
    4. DPulmonary artery
    💡 Explanation:

    The pulmonary artery is unusual in carrying deoxygenated blood, from the right ventricle to the lungs.

  41. Q41Past Paper · PPSC/FPSC/NTSeasy

    The largest artery in the human body is the

    1. AAorta
    2. BPulmonary artery
    3. CCarotid artery
    4. DRenal artery
    💡 Explanation:

    The aorta arises from the left ventricle and branches to supply blood to the entire body.

  42. Q42Past Paper · PPSC/FPSC/NTSmedium

    The valve located between the left atrium and left ventricle is the

    1. ATricuspid valve
    2. BPulmonary valve
    3. CAortic valve
    4. DBicuspid (mitral) valve
    💡 Explanation:

    The bicuspid or mitral valve has two flaps and prevents backflow of blood into the left atrium.

  43. Q43Past Paper · PPSC/FPSC/NTSeasy

    The iron-containing protein in red blood cells that carries oxygen is

    1. AMyosin
    2. BHemoglobin
    3. CCollagen
    4. DAlbumin
    💡 Explanation:

    Hemoglobin binds oxygen in the lungs and releases it to body tissues.

  44. Q44Past Paper · PPSC/FPSC/NTSmedium

    The universal blood recipient group is

    1. AAB positive
    2. BO negative
    3. CA negative
    4. DB positive
    💡 Explanation:

    AB positive blood has both A and B antigens plus Rh factor, so the plasma contains no antibodies against other ABO/Rh types.

  45. Q45Past Paper · PPSC/FPSC/NTSmedium

    The universal blood donor group is

    1. AO negative
    2. BAB positive
    3. CA positive
    4. DB negative
    💡 Explanation:

    O negative blood lacks A, B, and Rh antigens, so it can be given to recipients of any blood type in emergencies.

  46. Q46Past Paper · PPSC/FPSC/NTSeasy

    The functional and structural unit of the kidney is called

    1. AAlveolus
    2. BNeuron
    3. CNephron
    4. DVillus
    💡 Explanation:

    Each kidney contains about a million nephrons, which filter blood and form urine.

  47. Q47medium

    The heart chamber that pumps oxygenated blood to the rest of the body is the

    1. ARight atrium
    2. BLeft ventricle
    3. CRight ventricle
    4. DLeft atrium
    💡 Explanation:

    The left ventricle has the thickest muscular wall since it pumps blood at high pressure through the aorta to the whole body.

  48. Q48easy

    Blood vessels that carry blood away from the heart are called

    1. AVeins
    2. BCapillaries
    3. CArteries
    4. DVenules
    💡 Explanation:

    Arteries carry blood away from the heart, usually under high pressure.

  49. Q49medium

    Which blood cells are mainly responsible for clotting

    1. AErythrocytes
    2. BPlatelets (thrombocytes)
    3. CLeukocytes
    4. DLymphocytes
    💡 Explanation:

    Platelets aggregate at the site of injury and release factors that trigger the clotting cascade.

  50. Q50Past Paper · PPSC/FPSC/NTSeasy

    The number of chambers in the human heart is

    1. A2
    2. B3
    3. C5
    4. D4
    💡 Explanation:

    The human heart has four chambers: two atria and two ventricles.